First, DDIT4 overexpression upregulated PGC-1 and induced the expression of downstream TFAM in AML12 cells and primary hepatocytes regardless of APAP challenge (Fig
Epitalon-treated oocytes, however, showed reduced Annexin-V signals and a lower proportion of apoptotic cells, indicating that the peptide reduces apoptotic susceptibility in aged oocytes [2]
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